KMID : 0882420120830050624
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Korean Journal of Medicine 2012 Volume.83 No. 5 p.624 ~ p.628
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Granular Cell Tumor Originating from Gallbladder
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Kim Dong-Kyu
Jung Young-Kul Chung Dong-Hae Kim Hyung-Sik Kwon Oh-Sang Kim Yun-Soo Kim Ju-Hyun
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Abstract
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Granular cell tumors are rare benign tumors that arise from Schwann cells. They are especially rare in the gallbladder; indeed, only four cases have been reported in the English-language literature. This paper reports a granular cell tumor in the gallbladder and is the first such report in a Korean woman. She was admitted to the hospital with jaundice and fever and was diagnosed with acute hepatitis A. While hospitalized, a well-demarcated round mass was incidentally found in her gallbladder. The acute hepatitis A improved with conservative care, but the mass did not change in size after 4 months. The tumor was resected with the gallbladder during laparoscopic surgery, and was found to be a granular cell tumor. The tumor was composed of sheets or irregular fascicles of large polygonal or spindle cells with plump eosinophilic granular cytoplasm that was immunohistochemically positive for S-100 and neuron-specific enolase and negative for neurofilament.
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KEYWORD
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Gallbladder, Biliary tract, Granular cell tumor
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